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Regarding the vascular system, continuous infusion of the GLP-1 analog exendin-4 reduced monocyte adhesion to aortic endothelial cells, associated with a reduction in atherosclerotic lesion size in non-diabetic C57BL/6 and ApoE −/− mice
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It helps reduce joint pain and stiffness by supporting the natural production of cartilage components and lubricating joint surfaces
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