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The infrastructure is now being built: the CMS-0057-F rule mandates FHIR-based PA APIs by January 2027, AHIP pledges are driving operational improvements since January 2026, and the Medicare GLP-1 Bridge demonstration starting July 2026 will test centralized electronic PA at unprecedented scale
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At a high level, what appears to be most tangible about the experience of patients on GLP-1s is an abrupt reduction in cravings and compulsive behaviors and a sense of increased agency: the ability to make conscious decisions about what to consume, whether it is food or other substances, rather than feeling pulled by a strong internal urge
